Some of the best fiction comes from Appalachia; most likely, because of their storytelling habits. I've always been fascinated by folk medicine, maybe because it is similar to what my ancestors did in Louisiana. One of my ancestors was a traiteur, or faith healer. Granted, this is different from folk healing practices in Appalachia, yet both relied on medicinal plants and faith. Lately, its hard not to notice an explosion of taleneted Appalachian writers--authors like Amy Greene, Joni Agee, Ann Hite, Ron Rash, Wiley Cash, Robert Morgan, and Daniel Woodrell.
These novels aren't simply set in Appalachia but are informed by the setting. These characters couldn't have lived anywhere else. In many cases, the folk healing is a significant part of the story or other aspects of Appalachia--mining and its effects.
Folk medicine:
https://www.jstor.org/stable/40932250?seq=1#page_scan_tab_contents
One of my favorite Appalachian novels, The River Wife.
https://chantalreviews.blogspot.com/2012/10/the-river-wife-by-joni-agee.html
